Anti-MSH6 Polyclonal Antibody
品牌：solarbio | 货号：K006795P
| 英文名称 | Anti-MSH6 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | GTBP;HSAP;HNPCC5 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:10-50. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 153kDa |
| Gene ID | 2956 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human MSH6 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human MSH6 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P52701 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. |