Anti-LaminB Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-LaminB Polyclonal Antibody

品牌:solarbio | 货号:K106482P

英文名称 Anti-LaminB Polyclonal Antibody
宿主 Rabbit
别名 ADLD;LMN;LMN2;LMNB;LMNB1
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 66kDa
Gene ID 4001
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human LaminB
性状 液体
Public Immunogen Range A synthetic peptide of human LaminB
Subcellular Locations Intermediate filament Cell membrane Nucleus
Swiss Prot P20700
克隆类型 Polyclonal Antibody
背景资料 The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).