Anti-LaminB Polyclonal Antibody
品牌:solarbio | 货号:K106482P
英文名称 |
Anti-LaminB Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ADLD;LMN;LMN2;LMNB;LMNB1 |
应用 |
WB |
稀释比例 |
WB 1:3000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
66kDa |
Gene ID |
4001 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human LaminB |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human LaminB |
Subcellular Locations |
Intermediate filament Cell membrane Nucleus |
Swiss Prot |
P20700 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). |