Anti-PLA2G4A Polyclonal Antibody
品牌：solarbio | 货号：K006997P
| 英文名称 | Anti-PLA2G4A Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PLA2G4;cPLA2-alpha |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 85kDa |
| Gene ID | 5321 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PLA2G4A |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PLA2G4A |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P47712 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. |