Anti-COPS6 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-COPS6 Polyclonal Antibody

品牌:solarbio | 货号:K007303P

英文名称 Anti-COPS6 Polyclonal Antibody
宿主 Rabbit
别名 CSN6;MOV34-34KD
应用 IHC
稀释比例 IHC 1:20-100.
交叉反应 Human Mouse
蛋白分子量 36kDa
Gene ID 10980
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Full length fusion protein
性状 液体
Public Immunogen Range Full length fusion protein
Subcellular Locations Nucleus Cytoplasm
Swiss Prot Q7L5N1
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.?